Assay activity
2259029CA1 · ChEMBL activity 2259029
IC50 source measurement: = 3.04 uM. No cross-assay comparison is prequalified.
Not comparable: CONDITION_MISSING
Open the recordEvidence records
Release haca-evidence-v1-4bf3e75a91408390. 120 evidence records: 80 experimental structure mappings, 28 direct assay activities and 12 protein-specific reaction assignments. Each record lists every source it came from and, for measurements, the value exactly as the source reported it.
120 evidence records in this view, page 1 of 5.
Assay activity
2259048CA1 · ChEMBL activity 2259048
Ki source measurement: = 6.87 uM. No cross-assay comparison is prequalified.
Not comparable: CONDITION_MISSING
Open the recordExperimental structure
1AZMCA1 · PDB 1AZM
X-ray diffraction structure mapped through PDBe/SIFTS.
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1BZMCA1 · PDB 1BZM
X-ray diffraction structure mapped through PDBe/SIFTS.
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1CRMCA1 · PDB 1CRM
X-ray diffraction structure mapped through PDBe/SIFTS.
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1HCBCA1 · PDB 1HCB
X-ray diffraction structure mapped through PDBe/SIFTS.
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1J9WCA1 · PDB 1J9W
X-ray diffraction structure mapped through PDBe/SIFTS.
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2FOYCA1 · PDB 2FOY
X-ray diffraction structure mapped through PDBe/SIFTS.
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2NMXCA1 · PDB 2NMX
X-ray diffraction structure mapped through PDBe/SIFTS.
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3W6HCA1 · PDB 3W6H
X-ray diffraction structure mapped through PDBe/SIFTS.
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5E2MCA1 · PDB 5E2M
X-ray diffraction structure mapped through PDBe/SIFTS.
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6F3BCA1 · PDB 6F3B
X-ray diffraction structure mapped through PDBe/SIFTS.
Open the recordReaction assignment
RHEA:10748CA1 · RHEA:10748 assignment
Protein-specific UniProt catalytic-activity assignment joined to a balanced Rhea master reaction.
Open the recordAssay activity
18164781CA11 · ChEMBL activity 18164781
Ki source measurement: = 6.9 nM. No cross-assay comparison is prequalified.
Not comparable: CATALYTIC_STATUS_MISMATCH, CONDITION_MISSING
Open the recordAssay activity
1980545CA11 · ChEMBL activity 1980545
Kinact source measurement: = 5.7 nM. No cross-assay comparison is prequalified.
Not comparable: CATALYTIC_STATUS_MISMATCH, CONDITION_MISSING
Open the recordAssay activity
2456870CA12 · ChEMBL activity 2456870
Kinact source measurement: = 7.79 uM. No cross-assay comparison is prequalified.
Not comparable: CONDITION_MISSING
Open the recordAssay activity
2619636CA12 · ChEMBL activity 2619636
Ki source measurement: = 0.39 nM. No cross-assay comparison is prequalified.
Not comparable: CONDITION_MISSING
Open the recordExperimental structure
1JCZCA12 · PDB 1JCZ
X-ray diffraction structure mapped through PDBe/SIFTS.
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1JD0CA12 · PDB 1JD0
X-ray diffraction structure mapped through PDBe/SIFTS.
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4HT2CA12 · PDB 4HT2
X-ray diffraction structure mapped through PDBe/SIFTS.
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4KP5CA12 · PDB 4KP5
X-ray diffraction structure mapped through PDBe/SIFTS.
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4KP8CA12 · PDB 4KP8
X-ray diffraction structure mapped through PDBe/SIFTS.
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4Q0LCA12 · PDB 4Q0L
X-ray diffraction structure mapped through PDBe/SIFTS.
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6R71CA12 · PDB 6R71
X-ray diffraction structure mapped through PDBe/SIFTS.
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