Source assertion

PDBe/SIFTS maps PDB 3W6H to UniProt P00915 with chain-level identity and coverage retained.

Evidence ID: STRUCTURE:PDB:3W6H:UNIPROT:P00915
Subject dossier: ca1
Source chain: uniprot + pdbe
Upstream record: 3W6H
Corpus snapshot: 2026-07-14T09:23:31Z
Admission status: In this release

Experimental structure

Crystal structure of 19F probe-labeled hCAI in complex with acetazolamide

PDB ID: 3W6H
Experimental method: X-ray diffraction
Resolution: %!f(*float64=0x24b06affe8e0) Å
SIFTS identifier: CAH1_HUMAN
Deposited: 20130214
Released / revised: 20130313 / 20241016

Chain-level mapping

Entity	Chain	Structural asym	Identity	Coverage	UniProt range
1	`A`	`A`	100.0%	99.6%	2–261
1	`B`	`B`	100.0%	99.6%	2–261

Experimental constructs

Entity	Chains / asym IDs	Molecule	Length	Mutation flag	Preparation
1	A, B / A, B	Carbonic anhydrase 1polypeptide(L)	260 residues	not reported by the source	Genetically manipulated

Reading this structure

This is an experimentally determined structure, not a predicted model. A co-crystallised ligand, if any, does not by itself show binding affinity. The structure says nothing about kinetics, pathway rate or metabolic flux.

Snapshot provenance

Each row is a source snapshot this record was built from: when it was retrieved, its path and SHA-256 digest, and the exact request. The snapshot files stay with the build and are not served here. These rows document this record; they are not general citations.

Retrieved	Snapshot	SHA-256	Upstream request
2026-07-14T09:21:31Z	`raw/uniprot/entries/P00915.json`	`b3bde31c781c25e15bf68bd00c694f9b1027cdc49ec26688ca7d047de2a6ca95`	Open exact source
2026-07-14T09:21:37Z	`raw/pdbe/mappings/3w6h.json`	`e509d28f6814d00f97cebd2fa08f2b3ab3f37594283a948ffda30f6621636c5b`	Open exact source
2026-07-14T09:22:14Z	`raw/pdbe/summary/chunk-02.json`	`79ac3fb4e9e30c8c858b4d8ed8bbe6f85e8e0d0e3630627a999691f40a3d330d`	Open exact source
2026-07-14T09:22:14Z	`raw/pdbe/experiment/chunk-02.json`	`e42f681713cd9cdce851cc48738b3c6e0f0c075d0006a640c484bcab84561898`	Open exact source
2026-07-14T09:22:15Z	`raw/pdbe/molecules/chunk-02.json`	`27833f4d4cb9a9bfcb110f6e551fe2a5ccef01ccea4dda947132af6c51bd66e6`	Open exact source