Experimental structure
6RPSCA12 · PDB 6RPS
X-ray diffraction structure mapped through PDBe/SIFTS.
Open the recordEvidence records
Release haca-evidence-v1-4bf3e75a91408390. 120 evidence records: 80 experimental structure mappings, 28 direct assay activities and 12 protein-specific reaction assignments. Each record lists every source it came from and, for measurements, the value exactly as the source reported it.
120 evidence records in this view, page 2 of 5.
Reaction assignment
RHEA:10748CA12 · RHEA:10748 assignment
Protein-specific UniProt catalytic-activity assignment joined to a balanced Rhea master reaction.
Open the recordAssay activity
2949458CA13 · ChEMBL activity 2949458
Ki source measurement: = 32.0 nM. No cross-assay comparison is prequalified.
Not comparable: CONDITION_MISSING
Open the recordAssay activity
3380039CA13 · ChEMBL activity 3380039
Ki source measurement: = 79.0 nM. No cross-assay comparison is prequalified.
Not comparable: CONDITION_MISSING
Open the recordExperimental structure
3CZVCA13 · PDB 3CZV
X-ray diffraction structure mapped through PDBe/SIFTS.
Open the recordExperimental structure
3D0NCA13 · PDB 3D0N
X-ray diffraction structure mapped through PDBe/SIFTS.
Open the recordExperimental structure
3DA2CA13 · PDB 3DA2
X-ray diffraction structure mapped through PDBe/SIFTS.
Open the recordExperimental structure
4HU1CA13 · PDB 4HU1
X-ray diffraction structure mapped through PDBe/SIFTS.
Open the recordExperimental structure
4KNMCA13 · PDB 4KNM
X-ray diffraction structure mapped through PDBe/SIFTS.
Open the recordExperimental structure
4KNNCA13 · PDB 4KNN
X-ray diffraction structure mapped through PDBe/SIFTS.
Open the recordExperimental structure
5OGJCA13 · PDB 5OGJ
X-ray diffraction structure mapped through PDBe/SIFTS.
Open the recordReaction assignment
RHEA:10748CA13 · RHEA:10748 assignment
Protein-specific UniProt catalytic-activity assignment joined to a balanced Rhea master reaction.
Open the recordAssay activity
2456872CA14 · ChEMBL activity 2456872
Kinact source measurement: = 8.59 uM. No cross-assay comparison is prequalified.
Not comparable: CONDITION_MISSING
Open the recordAssay activity
2619658CA14 · ChEMBL activity 2619658
Ki source measurement: = 6.5 nM. No cross-assay comparison is prequalified.
Not comparable: CONDITION_MISSING
Open the recordExperimental structure
4LU3CA14 · PDB 4LU3
X-ray diffraction structure mapped through PDBe/SIFTS.
Open the recordExperimental structure
5CJFCA14 · PDB 5CJF
X-ray diffraction structure mapped through PDBe/SIFTS.
Open the recordReaction assignment
RHEA:10748CA14 · RHEA:10748 assignment
Protein-specific UniProt catalytic-activity assignment joined to a balanced Rhea master reaction.
Open the recordAssay activity
2259038CA2 · ChEMBL activity 2259038
IC50 source measurement: = 4.49 uM. No cross-assay comparison is prequalified.
Not comparable: CONDITION_MISSING
Open the recordAssay activity
2259058CA2 · ChEMBL activity 2259058
Ki source measurement: = 8.72 uM. No cross-assay comparison is prequalified.
Not comparable: CONDITION_MISSING
Open the recordAssay activity
2259064CA2 · ChEMBL activity 2259064
Ki source measurement: = 1.27 uM. No cross-assay comparison is prequalified.
Not comparable: CONDITION_MISSING
Open the recordAssay activity
2393950CA2 · ChEMBL activity 2393950
Ki source measurement: = 2.61 uM. No cross-assay comparison is prequalified.
Not comparable: CONDITION_MISSING
Open the recordExperimental structure
12CACA2 · PDB 12CA
X-ray diffraction structure mapped through PDBe/SIFTS.
Open the recordExperimental structure
1A42CA2 · PDB 1A42
X-ray diffraction structure mapped through PDBe/SIFTS.
Open the recordExperimental structure
1BCDCA2 · PDB 1BCD
X-ray diffraction structure mapped through PDBe/SIFTS.
Open the record