Source assertion

PDBe/SIFTS maps PDB 1JCZ to UniProt O43570 with chain-level identity and coverage retained.

Evidence ID: STRUCTURE:PDB:1JCZ:UNIPROT:O43570
Subject dossier: ca12
Source chain: uniprot + pdbe
Upstream record: 1JCZ
Corpus snapshot: 2026-07-14T09:23:31Z
Admission status: In this release

Experimental structure

CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN CARBONIC ANHYDRASE XII

PDB ID: 1JCZ
Experimental method: X-ray diffraction
Resolution: %!f(*float64=0x24b06afb15b0) Å
SIFTS identifier: CAH12_HUMAN
Deposited: 20010611
Released / revised: 20010817 / 20241120

Chain-level mapping

Entity	Chain	Structural asym	Identity	Coverage	UniProt range
1	`A`	`A`	100.0%	79.7%	29–291
1	`B`	`B`	100.0%	79.7%	29–291

Experimental constructs

Entity	Chains / asym IDs	Molecule	Length	Mutation flag	Preparation
1	A, B / A, B	Carbonic anhydrase 12polypeptide(L)	263 residues	not reported by the source	Genetically manipulated

Reading this structure

This is an experimentally determined structure, not a predicted model. A co-crystallised ligand, if any, does not by itself show binding affinity. The structure says nothing about kinetics, pathway rate or metabolic flux.

Snapshot provenance

Each row is a source snapshot this record was built from: when it was retrieved, its path and SHA-256 digest, and the exact request. The snapshot files stay with the build and are not served here. These rows document this record; they are not general citations.

Retrieved	Snapshot	SHA-256	Upstream request
2026-07-14T09:21:33Z	`raw/uniprot/entries/O43570.json`	`5e3bf6d20c857bc7f533ebfbfaf42d7ad6e84050aeb13c8f959567b94eb24d19`	Open exact source
2026-07-14T09:22:04Z	`raw/pdbe/mappings/1jcz.json`	`d41191530cc92f7487a19ad41485294c60de6a5dae815f3236e2a11f502f403e`	Open exact source
2026-07-14T09:22:12Z	`raw/pdbe/summary/chunk-01.json`	`dc1743d788d7927148f1208eac8f948637869ee61880999e81df1b79b57a0758`	Open exact source
2026-07-14T09:22:13Z	`raw/pdbe/experiment/chunk-01.json`	`fb047b9406db82cfc2256bd41ead50e4cd5ebf2ca5567e9be661676830294ed8`	Open exact source
2026-07-14T09:22:13Z	`raw/pdbe/molecules/chunk-01.json`	`4eb4d03de4d05f3f3a47f20fd76567c3ee5d6835db325358bbfe62bf45501b2a`	Open exact source