Biochemistry
Biomolecules · Catabolism · Biosynthesis · Metabolism
Metabolism map
Central metabolism
Reactome human metabolism as one network. Each reaction links to its Reactome record and each structure to ChEBI.
Explore
- Metabolism mapSearch, focus a pathway, or read any reaction’s page.
- MetabolitesPassports with structure, formula, compartments and pathways.
- CofactorsTwelve recurring cofactor systems and where they act.
Learn
- Mechanisms22 families and 97 ordered electron-flow moves.
- Flashcards323 cards, filtered by topic and depth.
- Study guides19 designed PDF guides.
- Field guideSixteen chapters on reading the map.
- NotebookNotes and bookmarks kept in this browser.
Isocitrate to 2-oxoglutarate
isocitrateoxidised by NADP⁺
oxalosuccinateβ-keto acid, loses CO₂
2-oxoglutarateenters the next step of the cycle
Isocitrate dehydrogenase: one arrow in the citric acid cycle on the map; the mechanism guide opens it into steps through the short-lived intermediate oxalosuccinate.
Evidence
- Evidence records120 source-linked records for the human carbonic anhydrases.
- Protein dossiers15 human α-carbonic anhydrases with structures and assays.
- Compare assaysRules for when two measurements can be compared.
- SourcesEvery upstream release, licence and digest.
Release haca-evidence-v1-4bf3e75a91408390: 15 human α-carbonic anhydrases, 80 experimental structure mappings, 28 direct assay activities and 12 protein-specific reaction assignments, each traced to its source record. How the family is defined
Data
- Public datasetsReactome human pathways and hierarchy, reviewed human enzymes from UniProt and recent metabolism papers, refreshed weekly.
- Release downloadsMap bundle, evidence corpus and comparison policy as JSON.