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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Amino-acid carbon

Amino-acid-specific transformations that connect carbon skeletons to central metabolism while preserving nitrogen handling as a separate question.

Branched-chain amino acids27 reactions, Reactome R-HSA-70895
Glutamate & glutamine14 reactions, Reactome R-HSA-8964539
Phenylalanine & tyrosine13 reactions, Reactome R-HSA-8963691
Tryptophan catabolism18 reactions, Reactome R-HSA-71240
Lysine catabolism16 reactions, Reactome R-HSA-71064
Histidine catabolism10 reactions, Reactome R-HSA-70921
Proline catabolism5 reactions, Reactome R-HSA-70688
Threonine catabolism2 reactions, Reactome R-HSA-8849175