Source assertion

PDBe/SIFTS maps PDB 4KNN to UniProt Q8N1Q1 with chain-level identity and coverage retained.

Evidence ID: STRUCTURE:PDB:4KNN:UNIPROT:Q8N1Q1
Subject dossier: ca13
Source chain: uniprot + pdbe
Upstream record: 4KNN
Corpus snapshot: 2026-07-14T09:23:31Z
Admission status: In this release

Experimental structure

Crystal structure of human carbonic anhydrase isozyme XIII with 2-Chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide

PDB ID: 4KNN
Experimental method: X-ray diffraction
Resolution: %!f(*float64=0x24b06affec50) Å
SIFTS identifier: CAH13_HUMAN
Deposited: 20130510
Released / revised: 20131106 / 20231108

Chain-level mapping

Entity	Chain	Structural asym	Identity	Coverage	UniProt range
1	`A`	`B`	100.0%	100.0%	1–262
1	`B`	`A`	100.0%	100.0%	1–262

Experimental constructs

Entity	Chains / asym IDs	Molecule	Length	Mutation flag	Preparation
1	A, B / A, B	Carbonic anhydrase 13polypeptide(L)	263 residues	not reported by the source	Genetically manipulated

Reading this structure

This is an experimentally determined structure, not a predicted model. A co-crystallised ligand, if any, does not by itself show binding affinity. The structure says nothing about kinetics, pathway rate or metabolic flux.

Snapshot provenance

Each row is a source snapshot this record was built from: when it was retrieved, its path and SHA-256 digest, and the exact request. The snapshot files stay with the build and are not served here. These rows document this record; they are not general citations.

Retrieved	Snapshot	SHA-256	Upstream request
2026-07-14T09:21:33Z	`raw/uniprot/entries/Q8N1Q1.json`	`606f7712a41abd05d3b9d0522bbefd377f44b400f37aba7cab2c788361ea41dd`	Open exact source
2026-07-14T09:22:09Z	`raw/pdbe/mappings/4knn.json`	`e4ce8b7c318416d39bb495098a6413beee4a2a1aeeec61821f4495b9d7f777a1`	Open exact source
2026-07-14T09:22:16Z	`raw/pdbe/summary/chunk-03.json`	`d318ed911ff2a8e3f25986a39c37baa2a3bb13c1d2a75d036924ca34ffa2b9cb`	Open exact source
2026-07-14T09:22:16Z	`raw/pdbe/experiment/chunk-03.json`	`8bbfae15de944b1cacdf21ee7a42caf9f09149a49b6fdf48f69df854b06973c9`	Open exact source
2026-07-14T09:22:17Z	`raw/pdbe/molecules/chunk-03.json`	`e94951408bdc68a6d0767211c754ae03dc74c4cf253ad3a7626c02d4aaba5eeb`	Open exact source