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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Serine metabolism

Serine synthesis and transformation, including transfer of one-carbon units to tetrahydrofolate. 8 reactions, from Reactome R-HSA-977347.

SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membraneL-Ser → L-Ser
PXLP-K56-SRR dimer deaminates D-SerD-Ser → PYR + NH4+
PXLP-K56-SRR dimer isomerises L-Ser to D-SerL-Ser → D-Ser
PXLP-K56-SRR dimer deaminates L-SerL-Ser → PYR + NH4+
PSPH:Mg2+ dimer dephosphorylates O-P-SerO-P-Ser + H2O → L-Ser + Pi
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA3POPA + L-Glu → 2OG + O-P-Ser
PHGDH tetramer dehydrogenates 3PG3PG + NAD+ → 3POPA + NADH + H+
SDS dimers:PXLP convert L-Ser to PYR and NH4+L-Ser → NH4+ + PYR