SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane
L-Ser → L-Ser
- Reactome
- R-HSA-8932980
- Compartment
- cytosol · plasma membrane
- Rhea
- RHEA:35031
Inputs
- L-SerCHEBI:33384, C3H7NO3, cytosol
Outputs
- L-SerCHEBI:33384, C3H7NO3, plasma membrane
Catalysed by
- molecular carrier activity of SERINC3,5,(1,2,4) [plasma membrane]
Literature
- Spotlight on HIV-1 Nef: SERINC3 and SERINC5 Identified as Restriction Factors Antagonized by the Pathogenesis Factor Viruses, 2015
- Serinc, an activity-regulated protein family, incorporates serine into membrane lipid synthesis J Biol Chem, 2005
- SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef Nature, 2015