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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane

L-Ser → L-Ser

Reactome
R-HSA-8932980
Compartment
cytosol · plasma membrane
Rhea
RHEA:35031

Inputs

Outputs

Catalysed by

  • molecular carrier activity of SERINC3,5,(1,2,4) [plasma membrane]

Literature

  1. Spotlight on HIV-1 Nef: SERINC3 and SERINC5 Identified as Restriction Factors Antagonized by the Pathogenesis Factor Viruses, 2015
  2. Serinc, an activity-regulated protein family, incorporates serine into membrane lipid synthesis J Biol Chem, 2005
  3. SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef Nature, 2015