Skip to content
DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
Data
100%

Loading the map…

PHGDH tetramer dehydrogenates 3PG

3PG + NAD+ → 3POPA + NADH + H+

Reactome
R-HSA-977348
Compartment
cytosol
Rhea
RHEA:12642

Inputs

Outputs

Catalysed by

  • phosphoglycerate dehydrogenase activity of PHGDH tetramer [cytosol]EC 1.1.1.95

Literature

  1. Novel mutations in 3-phosphoglycerate dehydrogenase (PHGDH) are distributed throughout the protein and result in altered enzyme kinetics Hum Mutat, 2009