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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Reversible CO₂ hydration

Compartment-specific interconversion of carbon dioxide and hydrogencarbonate by carbonic anhydrases. 8 reactions, from Reactome R-HSA-1475029.

Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a protonCO2 + H2O → H+ + HCO3-
Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxideH+ + HCO3- → CO2 + H2O
Carbonic anhydrase dehydrates bicarbonate (plasma membrane)H+ + HCO3- → CO2 + H2O
Carbonic anhydrase dehydrates bicarbonate (cytosol)H+ + HCO3- → CO2 + H2O
Carbonic anhydrase hydrates carbon dioxide (plasma membrane)CO2 + H2O → H+ + HCO3-
Carbonic anhydrase hydrates carbon dioxide (cytosol)CO2 + H2O → H+ + HCO3-
Carbonic anhydrase dehydrates bicarbonate (mitochondria)H+ + HCO3- → CO2 + H2O
Carbonic anhydrase hydrates carbon dioxide (mitochondria)CO2 + H2O → H+ + HCO3-