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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
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Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

CHAC1,2 cleaves GSH to OPRO and CysGly

GSH → OPRO + CysGly

Reactome: R-HSA-6785928
Compartment: cytosol
Rhea: RHEA:47725

Inputs

GSHCHEBI:57925, C10H16N3O6S, cytosol

Outputs

OPROCHEBI:58402, C5H6NO3, cytosol
CysGlyCHEBI:61694, C5H10N2O3S, cytosol

Catalysed by

glutathione specific gamma-glutamylcyclotransferase activity of CHAC1,2 [cytosol]EC 4.3.2.7

CHAC1,2 cleaves GSH to OPRO and CysGly

Inputs

Outputs

Catalysed by

Literature