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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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GSS:Mg2+ dimer synthesizes GSH

gGluCys + Gly + ATP → GSH + ADP + Pi

Reactome
R-HSA-174394
Compartment
cytosol
Rhea
RHEA:13558

Inputs

Outputs

Catalysed by

  • glutathione synthase activity of GSS:Mg2+ dimer [cytosol]EC 6.3.2.3

Literature

  1. Sequencing and expression of a cDNA for human glutathione synthetase Biochem J, 1995
  2. Molecular basis of glutathione synthetase deficiency and a rare gene permutation event EMBO J., 1999