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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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MTR transfers CH3 from MeCbl to HCYS

MTRR:MTR:MeCbl + HCYS → MTRR:MTR:cob(I)alamin + L-Met

Reactome
R-HSA-174374
Compartment
cytosol
Rhea
None recorded

Inputs

Outputs

Catalysed by

  • methionine synthase activity of MTRR:MTR:MeCbl [cytosol]EC 2.1.1.13

Literature

  1. Interaction of flavodoxin with cobalamin-dependent methionine synthase Biochemistry, 2000
  2. Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders Hum Mol Genet, 1996