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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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OPLAH hydrolyses OPRO to L-Glu

ATP + 2 H2O + OPRO → ADP + L-Glu + Pi

Reactome
R-HSA-1247935
Compartment
cytosol
Rhea
RHEA:10349

Inputs

Outputs

Catalysed by

  • 5-oxoprolinase (ATP-hydrolyzing) activity of OPLAH [cytosol]EC 3.5.2.9

Literature

  1. Characterization of 5-oxo-L-prolinase in normal and tumor tissues of humans and rats: a potential new target for biochemical modulation of glutathione Clin Cancer Res, 1998