About this dossier
UniProt-reviewed human alpha-carbonic-anhydrase scope record. This release admits five experimental structure mappings, two direct assay activities, and one protein-specific reaction assignment with record-local comparison boundaries retained. This release links 8 source records to this accession, a selection rather than every record the upstream databases hold.
Normalized identity
- Gene
- CA3
- UniProt accession
P07451- Catalytic status
- Catalytic
- Review state
- UniProt-reviewed
- Taxon
- 9606
- Entry version
- 226, updated 2026-06-10
- Sequence identity
- v3, CRC64
A305334167233FCF - Sequence length
- 260 residues
- Selected structures
- 5
- Selected activities
- 2
- Reaction assignments
- 1
- ChEMBL targets
- CHEMBL2885
Where the identity data came from
Each row is a UniProt snapshot used to build this release: when it was retrieved, its SHA-256 digest and the exact request. The snapshot files stay with the build and are not served here.
| Retrieved | Build-input snapshot | SHA-256 | Upstream request |
|---|---|---|---|
| 2026-07-14T09:21:32Z | raw/uniprot/entries/P07451.json | cf4d0cf96a6252efc608b8ee5c8b35b502dffa8996e6dbb74c6fa4b67ce3394f | Open exact source |
Source-reported location comments
- Cytoplasm
UniProt function text
Reversible hydration of carbon dioxide
Evidence records
Assay activityCA3 · ChEMBL activity 22506592250659, 2 comparison limitsAssay activityCA3 · ChEMBL activity 24568632456863, 1 comparison limitExperimental structureCA3 · PDB 1Z931Z93Experimental structureCA3 · PDB 1Z971Z97Experimental structureCA3 · PDB 2HFW2HFWExperimental structureCA3 · PDB 3UYN3UYNExperimental structureCA3 · PDB 3UYQ3UYQReaction assignmentCA3 · RHEA:10748 assignmentRHEA:10748