About this dossier
UniProt-reviewed human alpha-carbonic-anhydrase scope record. Seven experimental structure mappings, two direct assay activities, and one reaction assignment remain tied to CA13 rather than backfilled from nearby paralogs. This release links 10 source records to this accession, a selection rather than every record the upstream databases hold.
Normalized identity
- Gene
- CA13
- UniProt accession
Q8N1Q1- Catalytic status
- Catalytic
- Review state
- UniProt-reviewed
- Taxon
- 9606
- Entry version
- 181, updated 2026-06-10
- Sequence identity
- v1, CRC64
AE677F028ED729FE - Sequence length
- 262 residues
- Selected structures
- 7
- Selected activities
- 2
- Reaction assignments
- 1
- ChEMBL targets
- CHEMBL3912
Where the identity data came from
Each row is a UniProt snapshot used to build this release: when it was retrieved, its SHA-256 digest and the exact request. The snapshot files stay with the build and are not served here.
| Retrieved | Build-input snapshot | SHA-256 | Upstream request |
|---|---|---|---|
| 2026-07-14T09:21:33Z | raw/uniprot/entries/Q8N1Q1.json | 606f7712a41abd05d3b9d0522bbefd377f44b400f37aba7cab2c788361ea41dd | Open exact source |
Source-reported location comments
- Cytoplasm, cytosol
UniProt function text
Catalyzes the reversible conversion of carbon dioxide to hydrogencarbonate/bicarbonate and thus is essential in the regulation of pH and metabolic processes
Evidence records
Assay activityCA13 · ChEMBL activity 29494582949458, 1 comparison limitAssay activityCA13 · ChEMBL activity 33800393380039, 1 comparison limitExperimental structureCA13 · PDB 3CZV3CZVExperimental structureCA13 · PDB 3D0N3D0NExperimental structureCA13 · PDB 3DA23DA2Experimental structureCA13 · PDB 4HU14HU1Experimental structureCA13 · PDB 4KNM4KNMExperimental structureCA13 · PDB 4KNN4KNNExperimental structureCA13 · PDB 5OGJ5OGJReaction assignmentCA13 · RHEA:10748 assignmentRHEA:10748