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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

SLC25A20 exports excess acyl-CAR

Acyl-CAR + CAR → Acyl-CAR + CAR

Reactome: R-HSA-9971094
Compartment: mitochondrial inner membrane
Rhea: RHEA:49925

Inputs

Acyl-CARR-ALL-9971097, mitochondrial matrix
CARCHEBI:16347, C7H15NO3, mitochondrial intermembrane space

Outputs

Acyl-CARR-ALL-9971099, mitochondrial intermembrane space
CARCHEBI:16347, C7H15NO3, mitochondrial matrix

Catalysed by

carnitine:O-acyl-L-carnitine antiporter activity of SLC25A20 [mitochondrial inner membrane]UniProt O43772

Literature

Carnitine palmitoyltransferase II specificity towards beta-oxidation intermediates--evidence for a reverse carnitine cycle in mitochondria Eur J Biochem, 1998
Characterisation of carnitine palmitoyltransferases in patients with a carnitine palmitoyltransferase deficiency: implications for diagnosis and therapy J Neurol Neurosurg Psychiatry, 1997