GLYAT-like proteins transfer glycine to phenylacetyl-CoA
Gly + phenylacetyl-CoA → CoA-SH + phenylacetyl-Gly + H+
- Reactome
- R-HSA-9971063
- Compartment
- mitochondrial matrix
- Rhea
- RHEA:19870
Inputs
- GlyCHEBI:57305, C2H5NO2, mitochondrial matrix
- phenylacetyl-CoACHEBI:57390, C29H38N7O17P3S, mitochondrial matrix
Outputs
- CoA-SHCHEBI:57287, C21H32N7O16P3S, mitochondrial matrix
- phenylacetyl-GlyCHEBI:60874, C10H10NO3, mitochondrial matrix
- H+CHEBI:15378, H, mitochondrial matrix
Catalysed by
- glycine N-benzoyltransferase activity of GLYAT-like proteins [mitochondrial matrix]EC 2.3.1.71
Literature
- Purification to homogeneity of mitochondrial acyl coa:glycine n-acyltransferase from human liver Biochem Biophys Res Commun, 1994
- Designation of enzyme activity of glycine-N-acyltransferase family genes and depression of glycine-N-acyltransferase in human hepatocellular carcinoma Biochem Biophys Res Commun, 2012