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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

CPT1B transfers PALM to CAR

CAR + PALM-CoA → CoA-SH + L-PCAR

Reactome: R-HSA-9911362
Compartment: cytosol · mitochondrial outer membrane · mitochondrial intermembrane space
Rhea: RHEA:12661, RHEA:12662

Inputs

CARCHEBI:16347, C7H15NO3, mitochondrial intermembrane space
PALM-CoACHEBI:57379, C37H62N7O17P3S, cytosol

Outputs

CoA-SHCHEBI:57287, C21H32N7O16P3S, cytosol
L-PCARCHEBI:17490, C23H45NO4, mitochondrial intermembrane space

Catalysed by

carnitine O-palmitoyltransferase activity of CPT1B [mitochondrial outer membrane]EC 2.3.1.21; UniProt Q92523

Literature

Functional studies of yeast-expressed human heart muscle carnitine palmitoyltransferase I Arch Biochem Biophys, 1997