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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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CYP1A2 S-demethylates 6MMP

6MMP + NADPH + H+ + O2 → 6MP + H2O + CH2O + NADP+

Reactome: R-HSA-76386
Compartment: smooth endoplasmic reticulum
Rhea: None recorded

Inputs

6MMPCHEBI:28279, C6H6N4S, endoplasmic reticulum lumen
NADPHCHEBI:16474, C21H30N7O17P3, endoplasmic reticulum lumen
H+CHEBI:15378, H, endoplasmic reticulum lumen
O2CHEBI:15379, O2, endoplasmic reticulum lumen

Outputs

6MPCHEBI:2208, C5H4N4S, endoplasmic reticulum lumen
H2OCHEBI:15377, H2O, endoplasmic reticulum lumen
CH2OCHEBI:16842, CH2O, endoplasmic reticulum lumen
NADP+CHEBI:18009, C21H29N7O17P3, endoplasmic reticulum lumen

Catalysed by

monooxygenase activity of CYP1A2 [endoplasmic reticulum membrane]UniProt P05177