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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

XDH oxidizes xanthine to form urate

XAN + H2O + O2 → urate + H2O2

Reactome: R-HSA-74258
Compartment: cytosol
Rhea: RHEA:21133

Inputs

XANCHEBI:17712, C5H4N4O2, cytosol
H2OCHEBI:15377, H2O, cytosol
O2CHEBI:15379, O2, cytosol

Outputs

urateCHEBI:17775, C5H4N4O3, cytosol
H2O2CHEBI:16240, H2O2, cytosol

Catalysed by

xanthine oxidase activity of XDH dimer [cytosol]EC 1.17.3.2

XDH oxidizes xanthine to form urate

Inputs

Outputs

Catalysed by

Literature