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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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cytidine or uridine + ATP => CMP or UMP + ADP [UCK1]

Cyt-Rib, Ura-Rib + ATP → CMP, UMP + ADP + H+

Reactome
R-HSA-73599
Compartment
cytosol
Rhea
RHEA:24675, RHEA:16826

Inputs

Outputs

Catalysed by

  • nucleoside kinase activity of UCK1 tetramer [cytosol]

Literature

  1. Uridine kinase activities and pyrimidine nucleoside phosphorylation in fluoropyrimidine-sensitive and -resistant cell lines of the Novikoff hepatoma Biochem J, 1977
  2. Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases Mol Pharmacol, 2001