UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose
UTP + G1P + H+ → PPi + UDP-Glc
- Reactome
- R-HSA-70286
- Compartment
- cytosol
- Rhea
- RHEA:19890
Inputs
- UTPCHEBI:46398, C9H11N2O15P3, cytosol
- G1PCHEBI:58601, C6H11O9P, cytosol
- H+CHEBI:15378, H, cytosol
Outputs
- PPiCHEBI:33019, HO7P2, cytosol
- UDP-GlcCHEBI:58885, C15H22N2O17P2, cytosol
Catalysed by
- UTP:glucose-1-phosphate uridylyltransferase activity of 8xUGP2 [cytosol]EC 2.7.7.9
Literature
- Sequence differences between human muscle and liver cDNAs for UDPglucose pyrophosphorylase and kinetic properties of the recombinant enzymes expressed in Escherichia coli. Eur J Biochem, 1996
- Uridine diphosphate glucose pyrophosphorylase. IV. Crystallization and properties of the enzyme from human liver J Biol Chem, 1970
- Uridine diphosphate glucose pyrophosphorylase. II J Biol Chem, 1969