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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA

3Z-octenoyl-CoA → 2E-octenoyl-CoA

Reactome
R-HSA-6809808
Compartment
peroxisomal matrix
Rhea
RHEA:46045

Inputs

  • 3Z-octenoyl-CoACHEBI:85640, C29H44N7O17P3S, peroxisomal matrix

Outputs

  • 2E-octenoyl-CoACHEBI:62242, C29H44N7O17P3S, peroxisomal matrix

Catalysed by

  • delta(3)-delta(2)-enoyl-CoA isomerase activity of ECI2 trimer [peroxisomal matrix]EC 5.3.3.8

Literature

  1. Characterization of PECI, a novel monofunctional Delta(3), Delta(2)-enoyl-CoA isomerase of mammalian peroxisomes J. Biol. Chem., 1999
  2. Human Δ³,Δ²-enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10 FEBS J., 2015