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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
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Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
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Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

NUDT7 hydrolyses CoA-SH to 3',5'-ADP and PPANT

CoA-SH + H2O → PPANT + PAP + 2 H+

Reactome: R-HSA-6809354
Compartment: peroxisomal matrix
Rhea: RHEA:64989

Inputs

CoA-SHCHEBI:57287, C21H32N7O16P3S, peroxisomal matrix
H2OCHEBI:15377, H2O, peroxisomal matrix

Outputs

PPANTCHEBI:61723, C11H21N2O7PS, peroxisomal matrix
PAPCHEBI:58343, C10H11N5O10P2, peroxisomal matrix
2 H+CHEBI:15378, H, peroxisomal matrix

Catalysed by

coenzyme A diphosphatase activity of NUDT7 [peroxisomal matrix]EC 3.6.1.77; UniProt P0C024

NUDT7 hydrolyses CoA-SH to 3',5'-ADP and PPANT

Inputs

Outputs

Catalysed by

Literature