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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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ADPRM hydrolyses ADP-ribose to R5P and AMP

ADP-D-ribose + H2O → R5P + AMP + 2 H+

Reactome
R-HSA-5696049
Compartment
cytosol
Rhea
RHEA:10413

Inputs

Outputs

Catalysed by

  • ADP-ribose diphosphatase activity of ADPRM:Mn2+ [cytosol]EC 3.6.1.13

Literature

  1. Molecular bases of catalysis and ADP-ribose preference of human Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase and conversion by mutagenesis to a preferential cyclic ADP-ribose phosphohydrolase PLoS ONE, 2015