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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA

MCFA-CoA, LCFA-CoA + H2O → MCFA, LCFA + CoA-SH + H+

Reactome: R-HSA-5690042
Compartment: peroxisomal matrix
Rhea: RHEA:67681

Inputs

MCFA-CoA, LCFA-CoAR-ALL-5690520, peroxisomal matrix
H2OCHEBI:15377, H2O, peroxisomal matrix

Outputs

MCFA, LCFAR-ALL-5690539, peroxisomal matrix
CoA-SHCHEBI:57287, C21H32N7O16P3S, peroxisomal matrix
H+CHEBI:15378, H, peroxisomal matrix

Catalysed by

fatty acyl-CoA hydrolase activity of ACOT4,8 [peroxisomal matrix]EC 3.1.2.20

Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA

Inputs

Outputs

Catalysed by

Literature