OLAH hydrolyzes decanoyl-FASN dimer to DECA and FASN dimer
2 H2O + decanoyl-FASN dimer → 2 DECA + FASN dimer + 2 H+
- Reactome
- R-HSA-5655955
- Compartment
- cytosol
- Rhea
- RHEA:30116
Inputs
- 2 H2OCHEBI:15377, H2O, cytosol
- decanoyl-FASN dimerR-HSA-5655943, cytosol
Outputs
- 2 DECACHEBI:27689, C10H19O2, cytosol
- FASN dimerR-HSA-77380, cytosol
- 2 H+CHEBI:15378, H, cytosol
Catalysed by
- fatty acyl-[ACP] hydrolase activity of OLAH [cytosol]EC 3.1.2.14; UniProt Q9NV23
Literature
- Purification and properties of a thioesterase from lactating rat mammary gland which modifies the product specificity of fatty acid synthetase J. Biol. Chem., 1978
- Interaction of rat mammary gland thioesterase II with fatty acid synthetase is dependent on the presence of acyl chains on the synthetase J. Biol. Chem., 1987
- The fatty acids of human milk from mothers on diets taken ad libitum Biochem. J., 1959
- Triglyceride structure of human milk fat Can. J. Biochem., 1969