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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

SLC27A1 transports arachidonate across the ER membrane

AA → AA

Reactome: R-HSA-428990
Compartment: endoplasmic reticulum lumen · cytosol · endoplasmic reticulum membrane
Rhea: RHEA:71395

Inputs

AACHEBI:32395, C20H31O2, endoplasmic reticulum lumen

Outputs

AACHEBI:32395, C20H31O2, cytosol

Catalysed by

icosanoid transmembrane transporter activity of SLC27A1 [endoplasmic reticulum membrane]UniProt Q6PCB7

Literature

Impact on fatty acid metabolism and differential localization of FATP1 and FAT/CD36 proteins delivered in cultured human muscle cells Am J Physiol Cell Physiol, 2005
How is the level of free arachidonic acid controlled in mammalian cells? Biochem J, 1982
Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein Cell, 1994