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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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ACOX1 oxidizes C26:0 CoA

C26:0 CoA + O2 → trans-2,3-dehydrohexacosanoyl-CoA + H2O2

Reactome
R-HSA-390256
Compartment
peroxisomal matrix
Rhea
RHEA:78632

Inputs

Outputs

  • trans-2,3-dehydrohexacosanoyl-CoACHEBI:74281, C47H80N7O17P3S, peroxisomal matrix
  • H2O2CHEBI:16240, H2O2, peroxisomal matrix

Catalysed by

  • acyl-CoA oxidase activity of ACOX1 dimer [peroxisomal matrix]EC 1.3.3.6

Literature

  1. Overexpression and characterization of the human peroxisomal acyl-CoA oxidase in insect cells J Biol Chem, 1995
  2. Clinical, biochemical, and mutational spectrum of peroxisomal acyl-coenzyme A oxidase deficiency Hum Mutat, 2007