3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+
3-hydroxypristanoyl-CoA + NAD+ → 3-ketopristanoyl-CoA + NADH + H+
- Reactome
- R-HSA-389995
- Compartment
- peroxisomal matrix
- Rhea
- None recorded
Inputs
- 3-hydroxypristanoyl-CoACHEBI:63914, C40H72N7O18P3S, peroxisomal matrix
- NAD+CHEBI:57540, C21H26N7O14P2, peroxisomal matrix
Outputs
- 3-ketopristanoyl-CoACHEBI:57291, C40H66N7O18P3S, peroxisomal matrix
- NADHCHEBI:57945, C21H27N7O14P2, peroxisomal matrix
- H+CHEBI:15378, H, peroxisomal matrix
Catalysed by
- oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor of HSD17B4 dimer [peroxisomal matrix]EC 1.1.1
Literature
- Mutational spectrum of D-bifunctional protein deficiency and structure-based genotype-phenotype analysis Am J Hum Genet, 2006
- Purification and properties of human D-3-hydroxyacyl-CoA dehydratase: medium-chain enoyl-CoA hydratase is D-3-hydroxyacyl-CoA dehydratase J Biochem (Tokyo), 1996
- Structure of D-3-hydroxyacyl-CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein J Biochem, 1997