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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA

(2R) Pristanoyl-CoA → (2S) Pristanoyl-CoA

Reactome: R-HSA-389897
Compartment: peroxisomal matrix
Rhea: RHEA:40448

Inputs

(2R) Pristanoyl-CoACHEBI:77250, C40H68N7O17P3S, peroxisomal matrix

Outputs

(2S) Pristanoyl-CoACHEBI:77099, C40H68N7O17P3S, peroxisomal matrix

Catalysed by

racemase and epimerase activity of AMACR [peroxisomal matrix]EC 5.1; UniProt Q9UHK6

Literature

Purification and characterization of an alpha-methylacyl-CoA racemase from human liver Eur J Biochem, 1995
Mitochondrial and peroxisomal targeting of 2-methylacyl-CoA racemase in humans J Lipid Res, 2000
Subcellular localization and physiological role of alpha-methylacyl-CoA racemase J Lipid Res, 2000