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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)

(2S) Pristanoyl-CoA + O2 → trans-2,3-dehydropristanoyl-CoA + H2O2

Reactome: R-HSA-389891
Compartment: peroxisomal matrix
Rhea: RHEA:40460

Inputs

(2S) Pristanoyl-CoACHEBI:77099, C40H68N7O17P3S, peroxisomal matrix
O2CHEBI:15379, O2, peroxisomal matrix

Outputs

trans-2,3-dehydropristanoyl-CoACHEBI:77293, C40H66N7O17P3S, peroxisomal matrix
H2O2CHEBI:16240, H2O2, peroxisomal matrix

Catalysed by

pristanoyl-CoA oxidase activity of ACOX3:FAD [peroxisomal matrix]EC 1.3.3

Literature

Peroxisomal branched chain fatty acid beta-oxidation pathway is upregulated in prostate cancer Prostate, 2005
Evidence for the existence of a pristanoyl-CoA oxidase gene in man Biochem J, 1997