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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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GGT1, 5 dimers hydrolyse LTC4 to LTD4

LTC4 + H2O → LTD4 + L-Glu

Reactome
R-HSA-266046
Compartment
plasma membrane · extracellular region
Rhea
RHEA:31564

Inputs

Outputs

Catalysed by

  • glutathione gamma-glutamate hydrolase activity of GGT1, 5 dimers [plasma membrane]EC 3.4.19.13

Literature

  1. Interconversion of leukotrienes catalyzed by purified gamma-glutamyl transpeptidase: concomitant formation of leukotriene D4 and gamma-glutamyl amino acids Proc Natl Acad Sci U S A, 1982
  2. Gamma-glutamyl compounds: substrate specificity of gamma-glutamyl transpeptidase enzymes Anal Biochem, 2011