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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

LTD4 is converted to LTE4 by DPEP1/2

LTD4 + H2O → LTE4 + Gly

Reactome: R-HSA-266012
Compartment: plasma membrane · extracellular region
Rhea: RHEA:48617

Inputs

LTD4CHEBI:63166, C25H39N2O6S, extracellular region
H2OCHEBI:15377, H2O, extracellular region

Outputs

LTE4CHEBI:57462, C23H36NO5S, extracellular region
GlyCHEBI:57305, C2H5NO2, extracellular region

Catalysed by

dipeptidase activity of DPEP1,2 dimers [plasma membrane]EC 3.4.13.18

LTD4 is converted to LTE4 by DPEP1/2

Inputs

Outputs

Catalysed by

Literature