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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Prostaglandin E synthase isomerizes PGH2 to PGE2

PGH2 → PGE2

Reactome: R-HSA-265295
Compartment: cytosol
Rhea: RHEA:12894

Inputs

PGH2CHEBI:57405, C20H31O5, cytosol

Outputs

PGE2CHEBI:606564, C20H31O5, cytosol

Catalysed by

prostaglandin-E synthase activity of PTGES2(88-377), PTGES3 [cytosol]EC 5.3.99.3

Prostaglandin E synthase isomerizes PGH2 to PGE2

Inputs

Outputs

Catalysed by

Literature