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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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NUDT16 hydrolyses IDP to IMP

IDP + H2O → IMP + Pi + H+

Reactome
R-HSA-2509816
Compartment
nucleoplasm
Rhea
RHEA:35208

Inputs

Outputs

Catalysed by

  • IDP phosphatase activity of NUDT16 dimer [nucleoplasm]EC 3.6.1.64

Literature

  1. NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest Nucleic Acids Res., 2010
  2. Metal determines efficiency and substrate specificity of the nuclear NUDIX decapping proteins X29 and H29K (Nudt16) J. Biol. Chem., 2007