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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP

H2O + 8-oxo-dADP(3-) → Pi + 8-oxo-dAMP(2-) + H+

Reactome
R-HSA-2395965
Compartment
cytosol
Rhea
RHEA:35220

Inputs

Outputs

Catalysed by

  • 8-hydroxy-dADP phosphatase activity of NUDT18-1 [cytosol]UniProt Q6ZVK8

Literature

  1. Human MTH3 (NUDT18) Protein Hydrolyzes Oxidized Forms of Guanosine and Deoxyguanosine Diphosphates: COMPARISON WITH MTH1 AND MTH2 J. Biol. Chem., 2012