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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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ASA- acetylates PTGS2

PTGS2 dimer + ASA- → Ac-PTGS2 dimer + ST

Reactome
R-HSA-2314686
Compartment
cytosol · endoplasmic reticulum membrane
Rhea
None recorded

Inputs

Outputs

Literature

  1. Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin J. Biol. Chem., 1994
  2. Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimer J. Biol. Chem., 2011