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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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ASA- acetylates PTGS1

PTGS1 dimer + ASA- → Ac-PTGS1 dimer + ST

Reactome
R-HSA-2314678
Compartment
cytosol · endoplasmic reticulum membrane
Rhea
None recorded

Inputs

Outputs

Literature

  1. Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin J. Biol. Chem., 1994
  2. The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase Nat. Struct. Biol., 1995