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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

LTA4 is converted to EXA4 by ALOX15

LTA4 → EXA4

Reactome: R-HSA-2162019
Compartment: cytosol
Rhea: None recorded

Inputs

LTA4CHEBI:57463, C20H29O3, cytosol

Outputs

EXA4CHEBI:132070, C20H29O3, cytosol

Catalysed by

leukotriene-C4 synthase activity of ALOX15:Fe2+ [cytosol]EC 4.4.1.20

LTA4 is converted to EXA4 by ALOX15

Inputs

Outputs

Catalysed by

Literature