Skip to content

DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap

Data

Loading the map…

Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

5S-HpETE is reduced to 5S-HETE by GPX1/2/4

5S-HpETE + 2 GSH → 5S-HETE + GSSG + H2O

Reactome: R-HSA-2161946
Compartment: cytosol
Rhea: RHEA:48621

Inputs

5S-HpETECHEBI:57450, C20H31O4, cytosol
2 GSHCHEBI:57925, C10H16N3O6S, cytosol

Outputs

5S-HETECHEBI:90632, C20H31O3, cytosol
GSSGCHEBI:58297, C20H30N6O12S2, cytosol
H2OCHEBI:15377, H2O, cytosol

Catalysed by

glutathione peroxidase activity of GPX1/2/4 [cytosol]EC 1.11.1.9

Literature