EXC4 is converted to EXD4 by GGT
EXC4 → EXD4 + L-Glu
- Reactome
- R-HSA-2161945
- Compartment
- cytosol
- Rhea
- None recorded
Inputs
- EXC4CHEBI:63984, C30H47N3O9S, cytosol
Outputs
- EXD4CHEBI:747583, C25H39N2O6S, cytosol
- L-GluCHEBI:29985, C5H8NO4, cytosol
Catalysed by
- eoxin D4 synthase activity of GGT [cytosol]
Literature
- Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells Proc Natl Acad Sci U S A, 2008
- Hodgkin Reed-Sternberg cells express 15-lipoxygenase-1 and are putative producers of eoxins in vivo: novel insight into the inflammatory features of classical Hodgkin lymphoma FEBS J, 2008