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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
Data
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EXD4 is converted to EXE4 by DPEP

EXD4 + H2O → EXE4 + Gly

Reactome
R-HSA-2161868
Compartment
cytosol
Rhea
None recorded

Inputs

Outputs

Catalysed by

  • eoxin E4 synthase activity of DPEP [cytosol]

Literature

  1. Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells Proc Natl Acad Sci U S A, 2008
  2. Hodgkin Reed-Sternberg cells express 15-lipoxygenase-1 and are putative producers of eoxins in vivo: novel insight into the inflammatory features of classical Hodgkin lymphoma FEBS J, 2008