EXD4 is converted to EXE4 by DPEP
EXD4 + H2O → EXE4 + Gly
- Reactome
- R-HSA-2161868
- Compartment
- cytosol
- Rhea
- None recorded
Inputs
- EXD4CHEBI:747583, C25H39N2O6S, cytosol
- H2OCHEBI:15377, H2O, cytosol
Outputs
- EXE4CHEBI:747194, C23H36NO5S, cytosol
- GlyCHEBI:57305, C2H5NO2, cytosol
Catalysed by
- eoxin E4 synthase activity of DPEP [cytosol]
Literature
- Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells Proc Natl Acad Sci U S A, 2008
- Hodgkin Reed-Sternberg cells express 15-lipoxygenase-1 and are putative producers of eoxins in vivo: novel insight into the inflammatory features of classical Hodgkin lymphoma FEBS J, 2008