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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Arachidonate is converted to HXA3/B3 by ALOX12

AA + O2 → HXA3/B3

Reactome: R-HSA-2161794
Compartment: cytosol
Rhea: None recorded

Inputs

AACHEBI:32395, C20H31O2, cytosol
O2CHEBI:15379, O2, cytosol

Outputs

HXA3/B3R-ALL-2162031, cytosol

Catalysed by

hydroperoxy icosatetraenoate isomerase activity of ALOX12:Fe2+ [cytosol]EC 5.4.4.7

Arachidonate is converted to HXA3/B3 by ALOX12

Inputs

Outputs

Catalysed by

Literature