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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

EXA4 is converted to EXC4 by LTC4S

EXA4 + GSH → EXC4

Reactome: R-HSA-2161768
Compartment: cytosol · nuclear envelope
Rhea: None recorded

Inputs

EXA4CHEBI:132070, C20H29O3, cytosol
GSHCHEBI:57925, C10H16N3O6S, cytosol

Outputs

EXC4CHEBI:63984, C30H47N3O9S, cytosol

Catalysed by

eoxin C4 synthase activity of ALOX5:ALOX5AP:LTC4S [nuclear envelope]

EXA4 is converted to EXC4 by LTC4S

Inputs

Outputs

Catalysed by

Literature