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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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PGH2 is isomerised to PGD2 by HPGDS

PGH2 → PGD2

Reactome
R-HSA-2161701
Compartment
cytosol
Rhea
RHEA:10601

Inputs

Outputs

Catalysed by

  • prostaglandin-D synthase activity of HPGDS dimer [cytosol]EC 5.3.99.2

Literature

  1. Mammalian class Sigma glutathione S-transferases: catalytic properties and tissue-specific expression of human and rat GSH-dependent prostaglandin D2 synthases Biochem J, 2001
  2. Mechanism of metal activation of human hematopoietic prostaglandin D synthase Nat Struct Biol, 2003