Loading the map…

Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane

CAR + Acyl-CAR → CAR + Acyl-CAR

Reactome: R-HSA-200424
Compartment: mitochondrial intermembrane space · mitochondrial inner membrane · mitochondrial matrix
Rhea: RHEA:49916, RHEA:49926

Inputs

CARCHEBI:16347, C7H15NO3, mitochondrial matrix
Acyl-CARR-ALL-9971099, mitochondrial intermembrane space

Outputs

CARCHEBI:16347, C7H15NO3, mitochondrial intermembrane space
Acyl-CARR-ALL-9971097, mitochondrial matrix

Catalysed by

carnitine:O-acyl-L-carnitine antiporter activity of SLC25A20 [mitochondrial inner membrane]UniProt O43772

Literature

Cloning of the human carnitine-acylcarnitine carrier cDNA and identification of the molecular defect in a patient Am J Hum Genet, 1997