CYP11B2 oxidises 11DCORST to CORST
11DCORST + 2 NADPH + 2 H+ + O2 → CORST + H2O + 2 NADP+
- Reactome
- R-HSA-194017
- Compartment
- mitochondrial matrix · mitochondrial inner membrane
- Rhea
- RHEA:46105
Inputs
- 11DCORSTCHEBI:16973, C21H30O3, mitochondrial matrix
- 2 NADPHCHEBI:57783, C21H26N7O17P3, mitochondrial matrix
- 2 H+CHEBI:15378, H, mitochondrial matrix
- O2CHEBI:15379, O2, mitochondrial matrix
Outputs
- CORSTCHEBI:16827, C21H30O4, mitochondrial matrix
- H2OCHEBI:15377, H2O, mitochondrial matrix
- 2 NADP+CHEBI:58349, C21H25N7O17P3, mitochondrial matrix
Catalysed by
- steroid 11-beta-monooxygenase activity of CYP11B2 [mitochondrial inner membrane]EC 1.14.15.4; UniProt P19099